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    Seminar: High-throughput Computational Assessment of the Functional Impact of Protein Sequence Variations

    Event Details:

    • Date:          Tuesday, 13 December 2022
    • Time:         Starts: 16:00
    • Venue:       This is an online-only, public event. You may connect to our live stream of the discussion, available on Zoom (Password: VsSCz1)
    • Speaker:   Assoc. Professor Elodie Laine, Sorbonne Université



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    CaSToRC, the HPC National Competence Centre,
     invites you to the EuroCC and SimEA Seminar Series


     

    Abstract

    Identifying functional protein sites and understanding which and how genetic variations alter them are central questions for bioengineering, medicine, and fundamental biology. I will present three methods we recently developed in the team to assess the outcome of sequence variations on the interactions and functioning of proteins. They leverage the massive amounts of publicly available protein sequence and 3D structure information. Beyond predictive power, they provide interpretable outcomes and data representations.

    About the Speaker

    Elodie Laine works as an Associate Professor in the Laboratory of Computational and Quantitative Biology (LCQB), at Sorbonne Université (Paris, France). She did her PhD at Institut Pasteur and her post-doc at Ecole Normale Supérieure de Cachan, both in molecular modeling and structural bioinformatics. At LCQB, she has broaden her expertise to genomics, transcriptomics and protein evolution. She has been developing computational and artificial intelligence methods applicable at large scale to decipher the complexity of the protein sequence-structure-function relationship.

     

     

    Download the Fall 2022 EuroCC & SimEA Seminar Series Programme here.

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    The EuroCC project has received funding from the European Union’s Horizon 2020 research and innovation programme grant agreement No. 951732

    European Union's Horizon 2020 Research and Innovation Programme

    The SimEA project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 810660

     

     

    The seminar will be in English and the event is open to the public.
    This is an online-only, public event. You may connect to our live stream of the discussion, available on Zoom (Password: VsSCz1).
    Images and/or recordings of our open public events may be used by The Cyprus Institute for dissemination purposes including print and digital media such as websites, press-releases, social media, and live streaming.

     



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    Additional Info

    • Date: Tuesday, 13 December 2022
    • Time: Starts: 16:00
    • Speaker: Associate Professor Elodie Laine, Sorbonne Université, Paris, France

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